So far, several research groups have described about 40 DCM associated mutations in this gene.1–4 Heart disease caused by lamin A/C gene mutations is characterised by conduction system disorders with the need for permanent pacemaker implantation, atrial fibrillation, severe heart failure, and increased risk for sudden cardiac death.4 Patients with mutations in the lamin A/C gene often develop a progressive form of disease leading to heart transplantation or sudden cardiac death.4 Therefore, we decided to investigate a homogeneous group of consecutive Finnish heart transplant recipients with end stage DCM and to search for mutations in the lamin A/C gene.Īll surviving Finnish patients who received a heart transplant between 19 were enrolled in the study. Mutations in the lamin A/C gene seem to be important aetiological factors in familial DCM. Knowledge of the genetics of DCM has progressed considerably in recent years.1 At least one third of idiopathic DCM cases are familial. The aetiology and clinical presentation of DCM are heterogeneous.
REAMP WITH ID10V2 PRO
Compatible with iPad Air, iPad Air Wiâ?Fi + Cellular, iPad mini 2, iPad mini 2 Wiâ?Fi + Cellular, iPad Air 2, iPad Air 2 Wiâ?Fi + Cellular, iPad mini 3, iPad mini 3 Wiâ?Fi + Cellular, iPad mini 4, iPad mini 4 Wiâ?Fi + Cellular, iPad Pro (12.9â?inch), iPad Pro (12.9â?inch) Wi-Fi + Cellular, iPad Pro (9.7â?inch), iPad Pro (9.7â?inch) Wiâ?Fi + Cellular, iPad (5th generation), iPad (5th generation) Wiâ?Fi + Cellular, iPad Pro (12.9â?inch) (2nd generation), iPad Pro (12.9â?inch) (2nd generation) Wiâ?Fi + Cellular, iPad Pro (10.5â?inch), iPad Pro (10.5â?inch) Wiâ?Fi + Cellular, iPad (6th generation), iPad Wiâ?Fi + Cellular (6th generation), iPad Pro (11â?inch), iPad Pro (11â?inch) Wiâ?Fi + Cellular, iPad Pro (12.9â?inch) (3rd generation), iPad Pro (12.9â?inch) (3rd generation) Wiâ?Fi + Cellular, iPad mini (5th generation), iPad mini (5th generation) Wiâ?Fi + Cellular, iPad Air (3rd generation), iPad Air (3rd generation) Wiâ?Fi + Cellular, iPad (7th generation), iPad (7th generation) Wiâ?Fi + Cellular, iPad Pro (11â?inch) (2nd generation), iPad Pro (11â?inch) (2nd generation) Wiâ?Fi + Cellular, iPad Pro (12.9â?inch) (4th generation), and iPad Pro (12.9â?inch) (4th generation) Wiâ?Fi + Cellular.Dilated cardiomyopathy (DCM) is a primary myocardial disease characterised by impaired systolic function and dilatation of the left or both ventricles. NOTE! REAMP is an AUv3 plugin that only works in an AUv3 compliant host like Garageband, AUM, Cubasis, Beatmaker 3, Auria etc.Īdditional Requirements Requires iOS 9.1 or later. Seven handpicked profiles based on gear we love available.įull documentation available inside the app or at To prevent this, set the HARMONICS switch to SOME or FEW. Since were in the digital domain there can be some added aliasing when distorting the signal too much, resulting in an unpleasant high frequency boost. Another is to put it on the mix, or a bus.
One approach is to put it on several tracks with a more subtle setting which makes the essence of the gear simulated add upp. The output can span from lo-fi to high-end hifi. Since there are several models available, this one can be used on almost any type of audio in any genre. Tip: Run a Fender Jazz bass through it and your neo soul licks will sound just like theyre supposed to. One of the developers friends dad had an old bass amplifier that we borrowed and profiled. The guitar amp used is a well known pro amp used by several pro guitar players, and Just like the Preamp Tube profiles, these are recorded with two different input gain levels. Used on only one channel, this profile is very subtle, but the impact adds up when several channels are used simultaneously. These two profiles are captured from a high end tube microphone preamp with two different input gain levels (normal gain on the Clean version and a boosted level on the Drive version). Adds some subtle tape saturation that oozes mid 70s. Set to one channel mode, there was plenty of dynamic bandwidth to capture on this one. This profile adds some nice grit in the lower mids and rolls off the higher spectrum in a very pleasant way.Ī high quality tape reel machine was used for this profile. This data is used to transform input audio to output audio.Ī consumer cassette deck produced in the mid 80s. The 7 models available are based on real analog gear individually measured in two dimensions gain responses (-inf dB to +6 dB) at the frequency spectrum 20Hz to 20kHz. Benefits of this algorithm is that it is highly CPU efficient and adds (almost) no latency. This AUv3 plugin effect is a complex spectral saturation processor simulating a set of different analog gear in a new and unique way.
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